BIOL 1114 TCC Glioma Diagnosis and Treatment Lab and Discussion
BIOL 1114 TCC Glioma Diagnosis and Treatment Lab and Discussion
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Take Test: LAB 13 ANALYSIS LAB ( choose the best) 1. Open this link to open an article written in 2010 about diagnosis gliomas -http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910894/ The first five questions concern only this article. Which one of the following is true of the article? A. This article was written from a patient’s perspective. B. This article was written from a researcher’s perspective. C. This article was written from a clinician’s perspective. D. All of these are true. 2. Concerning the same article written in 2010 about diagnosis gliomas -http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910894/ FYI: Histological diagnosis involves creating slides of tumor tissue in a lab setting using specialized equipment. Pathologists look at these slides to make diagnoses. Read the abstract to answer this question. Studies show observers (in this case pathologists) vary in the way they type and grade glial tumors. Which of the following is true? A. This variation can result in both over- and undertreatment of glioma. B. The dosage of radiation is calculated from the type and grade of glioma. C. The use of chemotherapy is affected by the grade of glioma. D. All of these are true. 3. Same article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910894/ Use your mouse to hover over figure 1 or click the link to get full image. Which description is most accurate concerning Figure 1a? A. CT of the brain B. MRI of the brain C.-Stained glioma cells under a microscope of good quality D. Stained glioma cells under a microscope of poor quality 4. Read the first two sentences of the introduction. Which of the following is true? A. 500 brain tumor patients were reviewed by doctors and ≈50% doctors agreed on diagnoses, but none of the disagreements were serious B. 1,000 brain tumor patients were reviewed by computer programs and disagreement on diagnosing occurred 42.8% of the time, but only serious disagreement was reported in 8.8% of cases C. 500 brain tumor patients were reviewed by doctors and disagreement on diagnosing occurred 42.8% of the time, but only serious disagreement was reported in 8.8% of cases D. No reputable studies have been done concerning glioma diagnoses 5. Scroll all the way down to the final section of the article called Conclusion. Which of the following is NOT stated? A. Variation in the pathological diagnosis is a well-recognized and major issue in both the management of brain tumor patients and the conduct of clinical trials on brain tumors. B. More objective, quantitative and in particular reproducible histological criteria are urgently needed, as patient treatment, trial conduct and trial interpretation depend on the adequate selection of specific treatments for specific patients. C. If molecular criteria improve the classification of tumors, once validated these should be introduced into the WHO criteria for brain tumors – but there is no rush to make these changes D. . Routine review of the histological diagnosis of glioma by a second pathologist in daily clinical practice should be considered, preferably from an outside institution. 6. Open this article about glioblastoma treatment https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071154/ . Which of the following is true concerning the abstract? A. Patients are no longer receiving chemoradiotherapy with temozolomide. B. A tissue diagnosis remains the mainstay. C. Both of these are true. D. Neither of these are true. 7. From the Background section, mark the true statements. A. Glioblastoma is a fatal disease. B. Less than 5% of patients are alive at 5 years. C. Younger patients have the shortest survival time. D. The majority of patients die within 15–18 months of diagnosis. 8. In the first paragraph of the section Impact of molecular diagnostics, which is true of MGMT promoter methylation? A. It remains a predictor for chemotherapy response. B. It is significant in long-term survival. C. Both are true. D. Neither are true. Question and Answer. 9. From looking breifly at these two articles written 2010 and 2018, respectively, write 3-5 complete sentences concerning trends involving molecular diagnostics in gliomas. 10. Find an article about glioblastomas in NCBI PMC. Cut and paste a link or APA citation below to share your findings with me. Discussion Discussion: Simply the Best Discussion: Simply the Best Purpose We shouldn’t play favorites…but we all do. As we dive into ecology and communities, organismal interactions, and biodiversity, think about what your favorite organism has to offer. The purpose of this discussion is to get us thinking more broadly about how our favorite organisms affect all the others around them…and even some that are far away. Lesson Outcomes 1. Explore the interconnected nature of organisms in communities Steps to Complete the Task Step 1: Your Favorite Organism Open a Word document to draft your post. Then, you can copy/paste your completed post in Blackboard. This will help avoid any unexpected technical errors. 1. Choose one organism as your favorite. a. Describe this organism and why it is your favorite in a 2-sentence paragraph. 2. Describe what effects your favorite organism has on other organisms around it. a. Write a 3-5 sentence paragraph about how your organism interacts with or affects other organisms. Step 2: Post your Paragraphs You will post your discussion in the Unit 4 > 4. DISCUSS: Simply the Best Discussion. 1. Create a new thread and add your discussion. Do NOT attach the Word document. a. You are posting 2 paragraphs. Step 3: Reply to Classmates 1. Respond to a minimum of two classmates. 2. Read as many discussions as you have time to. 3. Find two peers who have interesting organisms or who may have posted inaccurate information. a. Do you believe their information is accurate? Why or why not? i. If no, do some research (Google or textbook) to support your point of view on the accuracy of the information and share it in your reply. ii. If yes, do some research (Google or textbook) to locate additional information on how the organism interacts with other organisms and share it in your reply. b. Be sure to identify your source (name and URL). Remember to always be courteous, especially if you choose to address someone’s information that is inaccurate. Be you should be humble and gentle in your response. In addition, know that the inaccurate information may be addressed in the course content. Criteria for Success To be successful, your discussion posts should: 1. Include one organism that is your favorite in Step 1 2. Include 3-5 sentences about interactions/effects between your organism and others. 3. Include thoughtful responses to two of your peers. a. Provide accurate information b. Include the name of the website and URL where you found your information
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