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Table 1: Ames test data for NCE1 –S9

Table 2: Ames test data for NCE1 +S9

Ames Test Data ( -S9)

Compound

Conc(μg/plate)TA1535 (mean revertantsper plate)TA1537(mean revertantsper plate)TA98 (mean revertantsper plate) TA100 (mean revertantsper plate) TA102 (mean revertantsper plate) Vehiclecontrol-10.08.045.0125.0260.0NCE150.011.012.055.0120.0250.0NCE1150.013.011.060.0135.0270.0NCE1300.09.07.099.0140.0265.0NCE11000.011.08.0165.0119.0290.0NCE15000.04.02.015.030.050.0Positive controlsVarious125.045.0250.01010.01300.0

Ames Test Data (-S9)

Compound Conc (μg/plate) TA1535 (mean revertants per plate) TA1537 (mean revertants per plate) TA98 (mean revertants per plate) TA100 (mean revertants per plate) TA102 (mean revertants per plate)
Vehicle control – 10.0 8.0 45.0 125.0 260.0
NCE1 50.0 11.0 12.0 55.0 120.0 250.0
NCE1 150.0 13.0 11.0 60.0 135.0 270.0
NCE1 300.0 9.0 7.0 99.0 140.0 265.0
NCE1 1000.0 11.0 8.0 165.0 119.0 290.0
NCE1 5000.0 4.0 2.0 15.0 30.0 50.0
Positive controls Various 125.0 45.0 250.0 1010.0 1300.0
Ames Test Data (+S9)

Compound

Conc(μg/plate)TA1535 (mean revertantsper plate)TA1537(mean revertantsper plate)TA98 (mean revertantsper plate) TA100 (mean revertantsper plate) TA102 (mean revertantsper plate) Vehiclecontrol-13.011.049.0140.0270.0NCE150.011.012.055.0129.0280.0NCE1150.015.014.052.0130.0290.0NCE1300.011.015.070.0140.0340.0NCE11000.012.09.0139.0150.0750.0NCE15000.07.06.030.039.0150.0Positive controlsVarious59.064.0520.0730.01700.0

Ames Test Data (+S9)

Compound Conc (μg/plate) TA1535 (mean revertants per plate) TA1537 (mean revertants per plate) TA98 (mean revertants per plate) TA100 (mean revertants per plate) TA102 (mean revertants per plate)
Vehicle control – 13.0 11.0 49.0 140.0 270.0
NCE1 50.0 11.0 12.0 55.0 129.0 280.0
NCE1 150.0 15.0 14.0 52.0 130.0 290.0
NCE1 300.0 11.0 15.0 70.0 140.0 340.0
NCE1 1000.0 12.0 9.0 139.0 150.0 750.0
NCE1 5000.0 7.0 6.0 30.0 39.0 150.0
Positive controls Various 59.0 64.0 520.0 730.0 1700.0