1. In a mating between a red-eyed male fruit fly and a red-eyed heterozygous female, what percentage of the female offspring is expected to be carriers? How did you determine the percentage?

1. In a mating between a red-eyed male fruit fly and a red-eyed heterozygous female, what percentage of the female offspring is expected to be carriers? How did you determine the percentage?

2. In a mating between a red-eyed male fruit fly and a white-eyed female fruit fly, what percentage of the male offspring will have white eyes? Describe how you determined the percentage.

3. Hemophilia, a blood disorder in humans, results from a sex-linked recessive allele. Suppose that a daughter of a mother without the allele and a father with the allele marries a man with hemophilia. What is the probability that the daughter’s children will develop the disease? Describe how you determined the probability.

4. Colorblindness results from a sex-linked recessive allele. Determine the genotypes of the offspring that result from a cross between a color-blind male and a homozygous female who has normal vision. Describe how you determined the genotypes of the offspring.

5. Explain why sex-linked traits appear more often in males than in females.

6. In humans, hemophilia is a sex-linked recessive trait. It is located on the X chromosome. Remember that the human female genotype is XX and the male genotype is XY. Suppose that a daughter of a mother without the allele and a father with the allele marries a man with hemophilia. What is the probability that the daughter’s children will develop the disease? Describe how you determined the probability.

7. Colorblindness also results from a sex-linked recessive allele on the X chromosome in humans. Determine the genotypes of the offspring that result from a cross between a color-blind male and a homozygous female who has normal vision. Describe how you determined the genotypes of the offspring.

8. Based on the traits explained in questions 6 and 7, explain why sex-linked traits in humans appear more often in males than in females.

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DNAandGenesWorkSheet1.doc